We are very lucky in this country to have a group of educated, informed individuals ensuring the safety of our food supply. Recent efforts by the Food and Drug Administration (FDA) Center for Veterinary Medicine have addressed reducing the use of "medically important" antibiotics in feeds given to food animals. The newest regulations increase the need for a VFD statement and are outlined in the FDA document referred to as "Guidance for Industry #213". The VFD Order is a written statement issued by a licensed veterinarian to the client (owner of the animal or animals, or other caretaker) to obtain and use animal feed containing a VFD drug. The VFD order is essentially, a document that acts similar to a prescription issued by a veterinarian that allows producers to include a medically important antibiotic in feed.

This regulation is specific to the feed or water supply containing the VFD drug, not to the type of animal that consumes this feed. The same regulation applies to dairy, deer and ducks. No animals are excluded. The regulations will affect all livestock producers regardless of operation size as of January 1, 2017 who wish to purchase feed grade antibiotics. Single animal owners and CAFOs (Concentrated Animal Feed Operations) fall under the same directive from the FDA. Keep in mind that extra-label use of feed grade antibiotics is not acceptable.

VFD orders have an expiration date and may indicate they are good for repeated purchases but may not exceed 6 months. Similar to a prescription, those "refills" will be limited. Education and understanding will fall on all animal owners, regardless of operation size or age. Livestock owners will have to be pro-active to prevent "gaps" in their feeding practices created by running low on medicated feed only to discover that the VFD has expired. Check your label for medically important drugs. These regulations reach into water soluble drugs that are transitioning from OTC (Over-the-counter) to prescription (Rx).

Hobby farmers or smaller operations associated with some 4-H and FFA participants may feel the impact of the regulations more than larger producers because smaller producers often obtain veterinary assistance only when there's a medical problem. Veterinarians who are already stretched too thin across some areas of Pennsylvania will have to make some adjustments for the increased VFD demand. The positive impact will be greater attention and understanding surrounding the use of medicated feeds and more responsibility on the part each animal owner to document medication use. The negative impact is the possibility of an increase in the number of sick and even dead animals especially where medicated feeds are a vital part of disease prevention.

Many 4-H and FFA participants have been advised to raise their animals using a preventative approach. Instead of waiting until animals get sick, the animals are fed antibiotics during periods of stress when they are most likely to get sick. Young animals are very susceptible to diseases when they are in the primary stages of life. Early in the infection progression, it can be difficult to detect the sickness and treat it in time to save the animal. This becomes a biosecurity issue as efforts will have to be stepped up to keep disease from spreading within the farm and to other farm families.

Inexperienced youth producers may be less likely to notice a disease in the early stages when a cure is most easily accomplished. Details such as reduced appetite or a listless gait could indicate the early onset of illness. Not all 4-H and FFA participants have the experience or observation skills to recognize these details. Even families who know what to look for, may find themselves in the "weekend window" or "holiday hold" where quickly obtaining a VFD or medicated feed order will be next to impossible.

The take home message here is be pro-active. Be deliberate in your observation of your animals. Track your observations in a journal or on a white board. Talk to your veterinarian and your feed mill and get a clear understanding of the procedure for getting a VFD. Veterinary practices will differ depending on staffing and technology for writing and transmitting a VFD. Above all, increase your biosecurity measures via best management practices that will decrease the risk of disease.

Pennsylvania State Department of Agriculture provides the following:
Effective January 1, 2017, a Veterinary Feed Directive (VFD) Order must be presented to purchase feeds containing the following medications.

Established Drug Name Examples of Proprietary Drug Names
Avilamycin* Kavault
Chlortetracycline (CTC) Aureomycin, CLTC, CTC, Chloratet, Chlorachel, ChlorMax, Chlortetracycline, Deracin, Inchlor, Pennchlor, Pfichlor
Chlortetracycline/Sulfamethazine Aureo S, Aureomix S, Pennchlor S
Chlortetracycline/Sulfamethazine/Penicillin Aureomix 500, Chlorachel/Pficlor SP, Pennchlor SP, ChlorMax SP
Florfenicol* Aquaflor, Nuflor
Hygromycin B Hygromix
Lincomycin Lincomix
Oxytetracycline (OTC) TM, OXTC, Oxytetracycline, Pennox, Terramycin
Oxytetracycline/Neomyicn Neo-Oxy, Neo-Terramycin
Penicillin Penicillin, Penicillin G Procaine
Sulfadimethoxine/Ormetoprim Rofenaid, Romet
Tilmicosin* Pulmotil, Tilmovet
Tylosin Tylan, Tylosin, Tylovet
Tylosin/Sulfamethazine Tylan Sulfa G, Tylan Plus Sulfa G, Tylosin Plus Sulfamethazine
Tylvalosin* Aivlosin
Virginiamycin Stafec, Virginiamycin, V-Max
* VFD Drug prior to January 1, 2017

Apramycin, Erythromycin, Neomycin (alone), Oleandomycin, Sulfamerazine, and Sulfaquinoxaline are also transitioning to VFD status, however they are not marketed at this time.

When a VFD drug is used in combination with a non-VFD drug, the feed would require a valid VFD prior to distribution to or use by the end-user.

*** According to Texas A&M Agrilife Extension Educators, the following drugs do not require a VFD at this time:

What drugs are not affected? (Most commonly used products listed)

Established Drug Name Examples
Injectable medications
No injectable projects affected
Ionophores
Monensin "Rumensin"
Anthelmetics Ivermectine, Fenbendazole "Safeguard"
Beta agonists
Ractopamine "Paylean"
Coccidiostats Decoquinate "Deccox"

References:

Food and Drug Administration. (n.d.). Antibiotics in Feed: An Exhibitor's Guide to the Veterinary Feed Directive [Brochure]. Author. Food and Drug Administration Center for Veterinary Medicine, http://www.agriculture.pa.gov/Protect/PlantIndustry/CommercialFeed/Documents/VFD Brochure.pdf found on December 8, 2017.

Pennsylvania State Department of Agriculture. (2016). VFD Notice [Brochure]. Harrisburg, PA: Author. David Dressler, http://www.agriculture.pa.gov/Pages/search.aspx?searchBox=antibiotics, August 11, 2016.

Texas A&M Agrilife Extension. (2016). Veterinary Feed Directive (VFD) Rule [Brochure]. Author. Retrieved December 8, 2016, from http://cooke.agrilife.org/veterinary-feed-directive-vfd-rule/
http://cooke.agrilife.org/files/2016/03/VFD-OTC-drugs-transitioning-to-RX-Water_1-19-16.pdf

United States, Department of Health and Human Services, Food and Drug Administration Center for Veterinary Medicine. (2013, December). Guidance for Industry #213. Retrieved December 9, 2016, from http://www.fda.gov/downloads/AnimalVeterinary/GuidanceComplianceEnforcement/GuidanceforIndustry/UCM299624.pdf

Veterinary Feed Directive [Brochure]. (n.d.). Retrieved December 8, 2016, from http://www.westcentralvet.com/documents/Veterinary Feed Directive.pdf

Written by Capri Stiles-Mikesell & Greg Strait, Penn State Extension Educators

Contact Information

Greg Strait
  • Agriculture and Youth Development/4-H Extension Educator